Antioxidants and Fibromyalgia? Let’s Talk!
Fibromyalgia a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. Researchers believe that fibromyalgia amplifies painful sensations by affecting the way your brain processes pain signals.
The exact cause of fibromyalgia continues to be an unfortunate mystery. However, studies have found correlations between glutathione levels, antioxidant levels, mitochondrial dysfunction and fibromyalgia.
- One study reported individuals with fibromyalgia have significantly lower levels of glutathione when compared to healthy controls
- Research has found evidence between oxidative stress and mitochondrial dysfunction in patients with fibromyalgia
- Individuals with fibromyalgia tend to show lower levels of antioxidants
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References
Sendur OF1, et al. Serum antioxidants and nitric oxide levels in fibromyalgia: a controlled study. Rheumatol Int. 2009 Apr;29(6):629-33. doi: 10.1007/s00296-008-0738-x. Epub 2008 Oct 14.
Okun JG1, et al. S-Acetylglutathione normalizes intracellular glutathione content in cultured fibroblasts from patients with glutathione synthetase deficiency. J Inherit Metab Dis. 2004;27(6):783-6. https://www.ncbi.nlm.nih.gov/pubmed/15617191
Cordero MD1, et al. Oxidative stress and mitochondrial dysfunction in fibromyalgia. Neuro Endocrinol Lett. 2010;31(2):169-73.
Nicolson GL. Mitochondrial Dysfunction and Chronic Disease: Treatment With Natural Supplements. Integrative Medicine: A Clinician’s Journal. 2014;13(4):35-43. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566449/